A meta-analysis reports a pooled Relative Risk (RR) of 0.75 (95% CI: 0.60–0.94) for a preventive intervention. This means the intervention:
- A Increases disease risk by 25%
- B Has no statistically significant effect
- C Reduces disease risk by 25% and the effect is statistically significant ✓
- D Reduces disease risk by 75%
Correct answer: C. Reduces disease risk by 25% and the effect is statistically significant
Explanation
An RR of 0.75 means those receiving the intervention have 75% the risk of the comparison group, representing a 25% relative risk reduction. Since the 95% CI (0.60–0.94) does not cross 1.0, the result is statistically significant at p < 0.05. Option D misreads the RR; Option A is incorrect because RR < 1 denotes reduction.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
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