Community Medicine (PSM) · Biostatistics (Measures of Central Tendency, Tests of Significance, Sampling)

A researcher finds a p-value of 0.03 in a study comparing two means. After applying Bonferroni correction for 10 simultaneous comparisons, the adjusted significance threshold is 0.005. The conclusion should be:

  • A The result remains statistically significant after correction
  • B The result is no longer statistically significant after correction
  • C Bonferroni correction is only applicable for non-parametric tests
  • D Multiple comparisons correction is unnecessary if a primary hypothesis was prespecified
Correct answer: B. The result is no longer statistically significant after correction

Explanation

With Bonferroni correction, the significance threshold is adjusted to α/n = 0.05/10 = 0.005. Since the p-value of 0.03 exceeds this threshold, the result is no longer statistically significant after correction. Bonferroni correction controls the family-wise error rate (FWER) by reducing Type I error (false positives) at the cost of increased Type II error (false negatives). It applies to both parametric and non-parametric tests when multiple comparisons are made.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.

Sponsored

Want to test yourself?

Create a free account for timed mock tests, mistake tracking, and FSRS spaced-repetition revision across 23,000+ MCQs.

Start free → Log in

More Biostatistics (Measures of Central Tendency, Tests of Significance, Sampling) MCQs

See all Biostatistics (Measures of Central Tendency, Tests of Significance, Sampling) MCQs →