A 10-year-old girl is brought for HPV vaccination. She has never received any dose previously. According to the IAP recommendations, what schedule should she receive?
- A Two doses, 6 months apart ✓
- B Three doses at 0, 1 and 6 months
- C Single dose, with a booster at 15 years
- D Two doses, 1 month apart
Correct answer: A. Two doses, 6 months apart
Explanation
For children vaccinated before 15 years of age, IAP recommends a two-dose HPV schedule with the second dose 6 months after the first, based on superior immunogenicity in this age group. The three-dose schedule is reserved for initiation at 15 years or older, or for immunocompromised individuals, which does not apply here. B 1-month interval is far too short to achieve adequate antibody response and is not part of any licensed HPV schedule.
Reference: IAP Guidebook on Immunization, Immunization Advisory Committee, 2023-2024 ed.
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