During a measles outbreak, a 7-month-old unvaccinated child is exposed to a confirmed measles case. What is the MOST appropriate immediate intervention?

• A Administer measles vaccine immediately as post-exposure prophylaxis
• B Start empirical ribavirin therapy
• C Isolate and observe; no intervention needed before 9 months
• D Administer normal human immunoglobulin within 6 days ✓

Explanation

For children under 6 months, immunocompromised individuals, and pregnant women exposed to measles who are susceptible, human immunoglobulin (IVIG 400 mg/kg or standard immunoglobulin 0.25 mL/kg IM) given within 6 days of exposure can prevent or attenuate disease. A 7-month-old is below the standard vaccine age but post-exposure immunization (as outbreak dose) can also be considered; however, passive immunoprophylaxis is the primary immediate intervention for very young infants.

Reference: Ghai Essential Pediatrics, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.