Pediatrics · Pediatric Immunization and Vaccines

A healthcare worker asks about the correct handling of the OPV vial during an immunization session. According to India's UIP open-vial policy, OPV vials that have been opened can be kept for use in subsequent sessions for a maximum of:

  • A 24 hours if refrigerated at 2–8°C
  • B 28 days if stored at 2–8°C and VVM has not reached discard point
  • C 4 weeks regardless of VVM status
  • D Must be discarded at end of every session without exception
Correct answer: B. 28 days if stored at 2–8°C and VVM has not reached discard point

Explanation

India's open-vial policy allows OPV vials to be retained for up to 28 days after opening, provided they remain at 2–8°C, the vaccine vial monitor (VVM) has not reached the discard point, the expiry date has not passed, and aseptic technique was maintained. OPV is among the multi-dose vaccines included in this policy (others include DPT, TT, Hep B, liquid formulations). This policy reduces vaccine wastage without compromising safety.

Reference: Ghai Essential Pediatrics, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.

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