Parents of a healthy 13-month-old child ask about protection against hepatitis A. The child has received all National Immunization Schedule vaccines. What is the CORRECT advice regarding hepatitis A vaccination?
- A A single dose of killed hepatitis A vaccine provides lifelong protection
- B Three doses of live attenuated hepatitis A vaccine at 0, 1 and 6 months
- C Two doses of killed hepatitis A vaccine, 6 months apart, starting now ✓
- D Vaccination should be deferred until 2 years of age because maternal antibodies neutralize the vaccine
Correct answer: C. Two doses of killed hepatitis A vaccine, 6 months apart, starting now
Explanation
IAP recommends universal hepatitis A vaccination with the killed (inactivated) vaccine given as two doses at least 6 months apart, beginning at or after 12 completed months of age. The live attenuated hepatitis A vaccine available in India is a single-dose product, so option B fails both on dose number and on the live claim. Maternal antibody interference is not a practical concern beyond 12 months, which removes the basis for deferring to 2 years.
Reference: IAP Guidebook on Immunization, Immunization Advisory Committee, 2023-2024 ed.
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Written and medically reviewed by the StethoPrep medical team.