Pediatrics · Pediatric Immunization and Vaccines

A preterm infant born at 30 weeks gestation is being discharged at 8 weeks chronological age. According to the National Immunization Schedule of India, which vaccines should be administered at this visit?

  • A DPT-Hib-IPV, OPV, Hepatitis B — as per chronological age (8 weeks)
  • B Delay all vaccines until 6 months corrected age
  • C BCG and Hepatitis B only
  • D Only inactivated vaccines; avoid live vaccines until 12 months corrected age
Correct answer: A. DPT-Hib-IPV, OPV, Hepatitis B — as per chronological age (8 weeks)

Explanation

Premature infants should receive immunizations according to their chronological (postnatal) age, not corrected/gestational age, as per IAP (Indian Academy of Pediatrics) and WHO guidelines. Most vaccines are immunogenic and well-tolerated in preterm infants when given at the standard chronological schedule. The exception is Hepatitis B: if birth weight <2 kg, the birth dose should not count toward the primary series. At 8 weeks chronological age, DPT-Hib-IPV, OPV, Hepatitis B (6-week dose), and Rotavirus vaccines are due.

Reference: Ghai Essential Pediatrics, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.

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