Regarding the varicella vaccine in the Indian Academy of Pediatrics (IAP) recommended schedule, which statement is MOST accurate?
- A Two doses are recommended: first at 15 months and second at 4–6 years ✓
- B Single dose at 15 months is sufficient for all children
- C Varicella vaccine is contraindicated in children with HIV on antiretrovirals
- D Varicella vaccine is a live attenuated vaccine but can be given to severely immunocompromised children
Correct answer: A. Two doses are recommended: first at 15 months and second at 4–6 years
Explanation
The IAP recommended schedule includes two doses of varicella vaccine: the first at 15 months and the second at 4–6 years (school entry). The two-dose schedule provides better protection (~98%) compared to one dose (~85%). The vaccine is a live attenuated vaccine and is generally contraindicated in severely immunocompromised children; however, HIV-infected children with CD4 ≥15% and no severe immunosuppression can receive it as the risk of natural varicella is very high. Single dose was previously used but two doses are now standard.
Reference: Ghai Essential Pediatrics, 10th ed.
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Written and medically reviewed by the StethoPrep medical team.