A 12-month-old child with HIV infection (CD4 count 800 cells/mm³, clinically asymptomatic, not on ART) requires MMR vaccination. The correct approach is:

• A Administer MMR; two doses are recommended with appropriate interval ✓
• B MMR is absolutely contraindicated in all HIV-infected children
• C Give only the measles component; avoid rubella in HIV
• D Delay MMR until CD4 count exceeds 1000 cells/mm³

Explanation

MMR is recommended for HIV-infected children who are not severely immunosuppressed. Per IAP and WHO, children with HIV and CD4 percentage ≥15% (or count ≥200 cells/mm³ for older children) can receive MMR in two doses; at 12 months this child has a CD4 count of 800 cells/mm³ (well above threshold), making vaccination appropriate. The vaccine is contraindicated only in severely immunocompromised HIV (CD4 <15% or <200 cells/mm³).

Reference: Ghai Essential Pediatrics, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.