Which of the following is the most common cause of nephrotic syndrome in adults?

• A Membranous nephropathy ✓
• B Minimal change disease
• C Focal segmental glomerulosclerosis
• D IgA nephropathy

Explanation

Membranous nephropathy is the most common cause of nephrotic syndrome in Caucasian and Indian adults, accounting for roughly 30 percent of adult cases. Minimal change disease is the most common cause in children but accounts for only 10 to 15 percent in adults. FSGS is increasing in incidence and is more frequent in Black populations. IgA nephropathy presents predominantly as nephritic syndrome or asymptomatic hematuria rather than frank nephrotic syndrome.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.