Y-chromosome STR haplotyping is unique among forensic DNA methods because it:
- A Is more discriminating than autosomal STRs for individual identification
- B Cannot differentiate males of the same patrilineal lineage ✓
- C Is maternally inherited and useful for female lineage reconstruction
- D Requires intact fresh tissue due to low copy number
Correct answer: B. Cannot differentiate males of the same patrilineal lineage
Explanation
The Y chromosome is passed unchanged from father to son (barring mutation), meaning all paternal relatives share the same Y-haplotype. This limits individual discrimination — a Y-haplotype cannot exclude a brother, uncle, or grandfather. It is therefore most useful for identifying male biological material in mixed samples and for establishing patrilineal kinship, not for definitive individual identification. Autosomal STRs remain superior for individual discrimination.
Reference: The Essentials of Forensic Medicine and Toxicology (Narayan Reddy), 34th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.