Histopathology of a papulosquamous lesion shows hypergranulosis, 'saw-tooth' rete ridges, basal cell liquefaction, Civatte bodies, and colloid bodies with band-like lymphocytic infiltrate hugging the epidermis. What is the diagnosis?
- A Psoriasis
- B Discoid lupus erythematosus
- C Lichen planus ✓
- D Pityriasis rosea
Correct answer: C. Lichen planus
Explanation
The histological triad of lichen planus is: irregular epidermal hyperplasia with saw-tooth rete ridges, hypergranulosis (prominent granular layer), and band-like subepidermal lymphocytic infiltrate with basal vacuolation and Civatte/colloid bodies (apoptotic keratinocytes). Psoriasis shows acanthosis, parakeratosis, suprapapillary thinning, and absence of granular layer. DLE shows follicular plugging and periadnexal inflammation.
Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.