Dermatology · Dermatopathology Patterns and Direct Immunofluorescence Interpretation

Histology of a psoriatic plaque shows regular elongation of rete ridges, suprapapillary thinning, parakeratosis and collections of neutrophils within the stratum corneum. These neutrophilic collections are called:

  • A Munro microabscesses
  • B Pautrier microabscesses
  • C Darier's nests
  • D Grenz zones
Correct answer: A. Munro microabscesses

Explanation

Munro microabscesses are collections of neutrophils in the stratum corneum (parakeratotic zone) and are a hallmark histological feature of psoriasis. They arise from neutrophil migration from dilated capillaries in the dermal papillae. Pautrier microabscesses are lymphocyte clusters within the epidermis in mycosis fungoides (CTCL). Grenz zones are acellular collagen-free bands seen below the epidermis in lepromatous leprosy and some granulomas.

Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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