Rosacea subtypes include erythematotelangiectatic, papulopustular, phymatous, and ocular variants. Which organism's eradication with oral ivermectin has shown efficacy specifically for the papulopustular subtype?
- A Demodex folliculorum ✓
- B Helicobacter pylori
- C Cutibacterium acnes
- D Staphylococcus epidermidis
Correct answer: A. Demodex folliculorum
Explanation
Demodex folliculorum, a hair follicle mite, is found in significantly elevated counts in rosacea patients, particularly the papulopustular subtype. Oral ivermectin (200 mcg/kg) reduces Demodex density and has demonstrated clinical efficacy in papulopustular rosacea in RCTs. Topical ivermectin 1% cream (Soolantra) is also approved. H. pylori eradication has variable and less convincing evidence for rosacea.
Reference: Neena Khanna Illustrated Synopsis of Dermatology & STD, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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