The fastigial nucleus of the cerebellum projects primarily to which target, and damage to this nucleus alone produces what clinical finding?
- A Red nucleus; contralateral limb dysmetria
- B Ventral lateral thalamus; ipsilateral limb intention tremor
- C Vestibular nuclei and reticular formation; truncal ataxia and gait imbalance ✓
- D Dentate nucleus; pendular reflexes
Correct answer: C. Vestibular nuclei and reticular formation; truncal ataxia and gait imbalance
Explanation
The fastigial nucleus is the output nucleus of the flocculonodular lobe (vestibulocerebellum) and projects to the ipsilateral and contralateral vestibular nuclei and reticular formation. Its damage causes truncal ataxia, gait disturbance, and balance problems because it integrates vestibular and postural information. The dentate nucleus (via the superior cerebellar peduncle) projects to the ventral lateral thalamus and red nucleus and is associated with limb dysmetria when damaged.
Reference: BD Chaurasia's Human Anatomy, 8th ed.
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