Anatomy · Neuroanatomy — Tracts, Nuclei and Lesion Localization (Advanced)

Occlusion of paramedian branches of the basilar artery at the pontine level causes ipsilateral abducens palsy, ipsilateral facial LMN palsy, and contralateral hemiplegia. This is known as:

  • A Weber syndrome
  • B Benedikt syndrome
  • C Parinaud syndrome
  • D Millard-Gubler syndrome
Correct answer: D. Millard-Gubler syndrome

Explanation

Millard-Gubler syndrome is a ventral pontine lesion affecting CN VI (abducens — ipsilateral lateral rectus palsy), CN VII (facial — ipsilateral LMN facial palsy), and the corticospinal tract (contralateral hemiplegia). Weber syndrome (midbrain) causes CN III palsy with contralateral hemiplegia. Benedikt syndrome involves the red nucleus causing contralateral tremor. Parinaud syndrome affects the dorsal midbrain causing upgaze palsy.

Reference: BD Chaurasia's Human Anatomy, 8th ed.

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