Anatomy · Histology (Epithelium, Connective Tissue, Bone, Muscle, Nerve)

On electron microscopy of a smooth muscle cell, intermediate filaments are anchored to dense bodies, which serve a function analogous to which structure in skeletal muscle?

  • A M line
  • B H zone
  • C A band
  • D Z line
Correct answer: D. Z line

Explanation

In smooth muscle, dense bodies anchor intermediate filaments and transmit contractile force, serving the same anchoring function as the Z line in skeletal muscle. The M line anchors thick myosin filaments. The A band contains overlapping actin and myosin, and the H zone is the central region of the A band containing only myosin.

Reference: Junqueira's Basic Histology, 16th ed.

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