Anatomy · Histology (Epithelium, Connective Tissue, Bone, Muscle, Nerve)

On electron microscopy of a skeletal muscle fibre the A-band is measured and found to be unchanged after passive stretching of the muscle. This is because the A-band represents:

  • A The entire length of the thin (actin) filaments
  • B The zone occupied solely by thin filaments with no myosin overlap
  • C The distance between two adjacent Z-discs
  • D The full length of thick (myosin) filaments, which does not change regardless of sarcomere length
Correct answer: D. The full length of thick (myosin) filaments, which does not change regardless of sarcomere length

Explanation

In the sliding filament model, the A-band corresponds to the full extent of the thick (myosin) filaments. Because myosin filaments do not change length during contraction or stretch, the A-band remains constant (~1.6 µm) regardless of sarcomere length. The I-band (thin filaments not overlapping myosin) and H-zone (central myosin without actin overlap) decrease during contraction and increase with stretch. The sarcomere length is the Z-disc-to-Z-disc distance and represents the full contractile unit.

Reference: BD Chaurasia's Human Anatomy, 8th ed.

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