A 28-year-old male with a painless right testicular mass has AFP 850 IU/mL, beta-hCG 12 mIU/mL, and LDH 1.5× ULN. CT shows retroperitoneal lymph nodes up to 2.5 cm and no visceral metastases. According to IGCCCG classification, this is which prognostic group?
- A Intermediate prognosis
- B Good prognosis ✓
- C Poor prognosis
- D Cannot classify without histology
Correct answer: B. Good prognosis
Explanation
The International Germ Cell Cancer Collaborative Group (IGCCCG) classifies non-seminomatous germ cell tumors (NSGCTs) as good prognosis if: testicular/retroperitoneal primary, no non-pulmonary visceral metastases, AND AFP <1000 IU/mL, beta-hCG <5000 mIU/mL, LDH <1.5× ULN. This patient meets all criteria — AFP 850 (<1000), beta-hCG 12 (<5000), LDH <1.5× ULN, no visceral metastases, testicular primary. Good prognosis carries ~95% 5-year survival with BEP chemotherapy.
Reference: Bailey & Love's Short Practice of Surgery, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.