Surgery · Urological Surgery (Kidneys, Bladder, Prostate, Urethra, Testis)

According to the D'Amico classification, a patient with PSA 7 ng/mL, Gleason score 3+4=7 (Grade Group 2), and clinical stage T2a prostate cancer falls into which risk category?

  • A Low risk
  • B High risk
  • C Very high risk
  • D Intermediate risk
Correct answer: D. Intermediate risk

Explanation

D'Amico classification for prostate cancer: Low risk — PSA <10, Gleason ≤6 (GG1), clinical stage T1-T2a; Intermediate risk — PSA 10-20 OR Gleason 7 (GG2-3) OR T2b; High risk — PSA >20 OR Gleason 8-10 (GG4-5) OR T2c/T3. This patient has Gleason 3+4=7 (GG2) which alone places them in the intermediate-risk category. Treatment options include radical prostatectomy or external beam radiotherapy with short-term androgen deprivation.

Reference: Bailey & Love's Short Practice of Surgery, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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