The RIFLE criteria and AKIN criteria for acute kidney injury stratification in a postoperative urology patient differ from the KDIGO 2012 definition. What serum creatinine rise within 48 hours defines AKI per KDIGO?
- A ≥50% rise from baseline within 7 days
- B Doubling of serum creatinine within 24 hours
- C ≥0.3 mg/dL (26.5 µmol/L) rise within 48 hours ✓
- D Serum creatinine >1.5 mg/dL in any context
Correct answer: C. ≥0.3 mg/dL (26.5 µmol/L) rise within 48 hours
Explanation
KDIGO 2012 defines AKI as any of: serum creatinine rise ≥0.3 mg/dL (26.5 µmol/L) within 48 hours; OR serum creatinine rise ≥1.5× baseline within 7 days; OR urine output <0.5 mL/kg/h for ≥6 consecutive hours. The 48-hour criterion of 0.3 mg/dL is more sensitive for early detection than earlier RIFLE/AKIN criteria. An absolute threshold of 1.5 mg/dL without baseline comparison is insufficient for AKI diagnosis, as patients with CKD have chronically elevated creatinine.
Reference: Bailey & Love's Short Practice of Surgery, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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