Surgery · Urological Surgery (Kidneys, Bladder, Prostate, Urethra, Testis)

The TNM 2017 staging for renal cell carcinoma classifies a tumour with direct invasion of the ipsilateral adrenal gland (contiguous extension, not by haematogenous spread) as:

  • A T3a
  • B T3b
  • C T4
  • D M1
Correct answer: C. T4

Explanation

In the TNM 2017 classification of RCC: T3a — invasion of renal vein or its segmental branches, or perirenal/sinus fat; T3b — tumour extends into vena cava below diaphragm; T3c — vena cava above diaphragm or into wall of cava; T4 — tumour invades beyond Gerota's fascia (including contiguous ipsilateral adrenal gland invasion). Non-contiguous adrenal metastasis is M1. This T4 designation carries poor prognosis and indicates tumour extension beyond the renal capsule's fascial boundary.

Reference: Bailey & Love's Short Practice of Surgery, 27th ed.

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