A 40-year-old woman presents with a 3 cm, well-circumscribed, mobile, rubbery breast lump that has been slowly growing over 3 years. Core biopsy shows a biphasic tumor with benign glandular elements and hypercellular stroma. There is no stromal overgrowth or atypia. What is the recommended surgical management?

• A Observation with follow-up
• B Simple mastectomy
• C Radical mastectomy
• D Wide local excision with 1 cm margins ✓

Explanation

D benign phyllodes tumor is treated with wide local excision with at least 1 cm margins to prevent local recurrence. Simple mastectomy is reserved for very large tumors where adequate margins cannot be achieved with breast conservation. Radical mastectomy is unnecessary, and observation is inappropriate given the size and growth.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.