Which classification system specifically stratifies phyllodes tumours of the breast into benign, borderline, and malignant based on stromal cellularity, mitotic rate, nuclear pleomorphism, stromal overgrowth, and tumour borders?
- A WHO Classification of Tumours of the Breast ✓
- B Nottingham Grading System
- C Scarff-Bloom-Richardson system
- D Van Nuys Prognostic Index
Correct answer: A. WHO Classification of Tumours of the Breast
Explanation
The WHO Classification of Tumours of the Breast defines three grades of phyllodes tumour (benign, borderline, malignant) using five histological criteria: stromal cellularity, stromal atypia, mitotic count, stromal overgrowth, and tumour border characteristics. The Nottingham and Scarff-Bloom-Richardson systems grade invasive carcinoma. The Van Nuys Prognostic Index applies to DCIS.
Reference: Bailey & Love's Short Practice of Surgery, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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