Wilson and Jungner (1968) criteria for screening require that 'The natural history of the condition, including development from latent to declared disease, should be adequately understood.' This criterion primarily ensures that:
- A The test has high sensitivity
- B There is a detectable latent or early symptomatic stage amenable to intervention ✓
- C Treatment at the latent stage is available and proven
- D The disease carries high case fatality if untreated
Correct answer: B. There is a detectable latent or early symptomatic stage amenable to intervention
Explanation
Understanding the natural history of disease is essential to ensure there exists a recognizable latent or early symptomatic stage during which detection is possible and intervention is beneficial. Without a detectable preclinical phase, screening cannot identify patients before clinical presentation. Knowing the natural history also helps define the optimal screening interval and target age group.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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