Community Medicine (PSM) · Screening of Diseases and Health Concepts

A test has sensitivity 90% and specificity 85%. The Likelihood Ratio of a Positive test (LR+) is:

  • A 6.0
  • B 3.0
  • C 9.0
  • D 10.5
Correct answer: A. 6.0

Explanation

LR+ = Sensitivity / (1 – Specificity) = 0.90 / 0.15 = 6.0. LR+ >10 provides strong diagnostic evidence; 5–10 moderate; 2–5 small; <2 minimal. An LR+ of 6 means a positive test result is 6 times more likely to occur in a truly diseased person than in a healthy one. LR+ is used with Bayes' theorem to update pre-test probability to post-test probability using nomograms or Fagan's plot.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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