Byssinosis is an occupational lung disease seen in cotton textile workers. Which of the following BEST describes the characteristic symptom pattern of byssinosis?

• A Progressive breathlessness that is worse at the end of the workweek
• B Persistent cough and breathlessness unrelated to workdays
• C Episodic wheezing exclusively occurring during nights and weekends
• D Chest tightness and breathlessness on the FIRST day back at work after a weekend break, which improves during the week ✓

Explanation

The hallmark of byssinosis is 'Monday fever' or 'Monday dyspnea'—chest tightness and breathlessness characteristically occurring on the first day of the workweek (Monday) after a break, caused by cotton dust inhalation. Symptoms improve as the week progresses (tachyphylaxis). In advanced stages, symptoms persist throughout the week. This pattern distinguishes byssinosis from asthma and other occupational lung diseases. The causative agent is endotoxin from Gram-negative bacteria contaminating raw cotton.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.