Under India's Universal Immunization Programme, Inactivated Polio Vaccine (IPV) is administered as fractional intradermal doses. What is the correct dose, route, and schedule for IPV under the NIS?

• A 0.5 mL intramuscular at 6 weeks only
• B 0.1 mL intradermal at 6 weeks only
• C 0.5 mL subcutaneous at 6 weeks and 14 weeks
• D 0.1 mL intradermal at 6 and 14 weeks ✓

Explanation

Under India's UIP, IPV is given as two fractional doses of 0.1 mL each by the intradermal route at 6 weeks and 14 weeks of age. The fractional intradermal dose (one-fifth of the IM dose) is immunogenic and cost-effective, allowing wider coverage with limited supply. This strategy was adopted to provide injectable polio protection alongside OPV in the endgame polio eradication strategy.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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