A health worker at a PHC is preparing to reconstitute a freeze-dried BCG vaccine before an immunization session. Which diluent should be used, and how should it be stored before use?
- A Normal saline (0.9% NaCl); stored cold at 2-8°C alongside the vaccine ✓
- B Sterile water for injection; stored frozen at -20°C
- C DistilIed water; stored at room temperature
- D Diluent provided with the vaccine; stored at ambient temperature
Correct answer: A. Normal saline (0.9% NaCl); stored cold at 2-8°C alongside the vaccine
Explanation
BCG vaccine is freeze-dried and must be reconstituted with the specific diluent provided, which for BCG is normal saline (0.9% NaCl). The diluent should be stored cold (2-8°C) alongside the vaccine in the ILR. Using sterile water or distilled water can damage the live attenuated bacilli. The diluent must never be frozen. Always use only the diluent supplied by the manufacturer with that specific vaccine lot.
Reference: :Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.