Which of the following correctly describes inactivated poliovirus vaccine (IPV) administration under India's National Immunization Schedule?

• A Full dose (0.5 mL) intramuscularly at 6, 10 and 14 weeks
• B Single full dose (0.5 mL) intramuscularly at 9 months
• C Fractional dose (0.1 mL) subcutaneously at 6 and 14 weeks
• D Fractional dose (0.1 mL) intradermally at 6 and 14 weeks ✓

Explanation

India introduced fractional IPV (fIPV) as 0.1 mL by the intradermal route at 6 and 14 weeks, given concurrently with oral poliovirus vaccine. This two-dose fractional schedule was adopted to conserve antigen supply while providing mucosal priming plus humoral immunity through OPV co-administration. The route is intradermal, not subcutaneous, and three full dose IPV schedules are not what the national programme uses.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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