A medical officer is orienting staff on the fractional dose of IPV used in the National Immunization Schedule. Which combination of dose, route and scheduled ages is correct for fractional IPV?
- A 0.1 mL intradermal at 6 and 14 weeks ✓
- B 0.5 mL intramuscular at 6 and 10 weeks
- C 0.1 mL subcutaneous at 10 and 14 weeks
- D 0.5 mL intradermal at birth and 6 weeks
Correct answer: A. 0.1 mL intradermal at 6 and 14 weeks
Explanation
Fractional IPV is 0.1 mL given intradermally, one fifth of the full 0.5 mL intramuscular dose, at 6 and 14 weeks, administered in opposite arms relative to pentavalent. The fractional schedule was adopted to conserve global IPV supply while priming against type 2 poliovirus after the switch from tOPV to bOPV. The full 0.5 mL intramuscular dose belongs to the pre-fractional schedule and catch-up campaigns, not routine fIPV sessions.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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