Under the National Immunization Schedule, Japanese encephalitis vaccine is administered in endemic districts. Which statement about this vaccine is correct?
- A Live attenuated 17D strain, single dose at 12 months, subcutaneous route
- B Inactivated mouse brain-derived vaccine, two doses at 6 and 14 weeks, intramuscular route
- C Live attenuated SA 14-14-2 strain, single dose at 9 to 12 months, subcutaneous route ✓
- D Recombinant protein vaccine, two doses at 9 and 16 to 18 months, intramuscular route
Correct answer: C. Live attenuated SA 14-14-2 strain, single dose at 9 to 12 months, subcutaneous route
Explanation
India uses the live attenuated SA 14-14-2 JE vaccine (JENVAC lineage, originally the Chinese CD.JE strain), given as a single 0.5 mL subcutaneous dose at 9 to 12 months along with MR vaccine in endemic districts, with campaign catch-up up to 15 years. The 17D strain is yellow fever vaccine, not JE. The older mouse brain inactivated vaccine has been discontinued from routine use due to reactogenicity.
Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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