Community Medicine (PSM) · Immunization and Vaccines (Cold Chain, NIS Schedule, Open Vial Policy)

Before loading a vaccine carrier for an outreach session, the health worker removes ice packs from the freezer. Why must the ice packs be conditioned before being placed in the carrier?

  • A To prevent freezing of freeze-sensitive vaccines such as hepatitis B and pentavalent
  • B To increase the cold life of the carrier beyond 12 hours
  • C To melt excess water so the carrier does not become heavy
  • D To activate the VVM on the vials placed inside
Correct answer: A. To prevent freezing of freeze-sensitive vaccines such as hepatitis B and pentavalent

Explanation

Ice packs straight from the freezer are well below 0 degrees C and can freeze vaccines touching them. Conditioning means leaving the ice packs at room temperature until the ice core moves freely inside the pack, raising their surface toward 0 degrees C. This protects freeze-sensitive vaccines like hepatitis A, DPT, TT and pentavalent while still keeping the carrier within 2 to 8 degrees C. Conditioning does not extend cold life and has nothing to do with the VVM.

Reference: WHO Immunization in Practice, 2015 update ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.

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