Community Medicine (PSM) · Immunization and Vaccines (Cold Chain, NIS Schedule, Open Vial Policy)

The Open Vial Policy (OVP) under UIP allows multi-dose vials of which vaccine to be USED at subsequent sessions (not discarded) if certain conditions are met?

  • A Oral Polio Vaccine (OPV) but not reconstituted vaccines
  • B BCG and measles-rubella (MR) vaccines after reconstitution
  • C Pentavalent, PCV, Rotavirus, IPV, TT — liquid vaccines not needing reconstitution
  • D All UIP vaccines without exception
Correct answer: C. Pentavalent, PCV, Rotavirus, IPV, TT — liquid vaccines not needing reconstitution

Explanation

India's Open Vial Policy applies to liquid, multi-dose vaccines that do NOT require reconstitution: Oral Polio Vaccine, Pentavalent, PCV, Rotavirus, IPV, Hepatitis B, and TT. Opened vials of these vaccines can be used at subsequent sessions within 28 days (for vials that meet the storage, VVM, and no-contamination conditions). BCG and MR vaccines require reconstitution; once reconstituted, they must be discarded within 4 hours (BCG) or at the end of the session (MR) — they are NOT covered by OVP. This distinction is high-yield.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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