Community Medicine (PSM) · Immunization and Vaccines (Cold Chain, NIS Schedule, Open Vial Policy)

The Open Vial Policy applies to certain vaccines under UIP. A multi-dose vial of OPV that was opened during an immunisation session can be used in subsequent sessions within how many days if stored correctly at 2–8°C?

  • A 28 days
  • B 7 days
  • C 3 days
  • D Single session use only — must discard after session
Correct answer: A. 28 days

Explanation

Under the Open Vial Policy (OVP), OPV multi-dose vials can be used for up to 28 days after opening provided the cold chain is maintained (2–8°C), the VVM has not reached discard point, the vial is not expired, and no contamination has occurred (aseptic technique maintained). This policy contrasts with vaccines like BCG which must be discarded within 3 hours, and measles/MMR which should be discarded at end of session. OVP prevents wastage of OPV, which accounts for a significant proportion of cold chain load.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

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