Community Medicine (PSM) · Immunization and Vaccines (Cold Chain, NIS Schedule, Open Vial Policy)

The Open Vial Policy (OVP) allows multi-dose vaccine vials to be used across multiple sessions. Which vaccine is EXCLUDED from the Open Vial Policy?

  • A Measles-Rubella (MR) vaccine after reconstitution
  • B Oral Poliovirus Vaccine (OPV)
  • C DPT (whole-cell pertussis)
  • D Hepatitis B vaccine
Correct answer: A. Measles-Rubella (MR) vaccine after reconstitution

Explanation

The Open Vial Policy applies to vaccines that do not require reconstitution (e.g., OPV, DPT, Hepatitis B, TT) and allows opened multi-dose vials to be used for up to 28 days if kept at correct temperature and not contaminated. Reconstituted vaccines (MR, BCG, Varicella, Yellow Fever) must be discarded within 6 hours or at end of session, as reconstitution introduces contamination risk and stability of freeze-dried vaccines changes after reconstitution.

Reference: Park's Textbook of Preventive and Social Medicine, 27th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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