A 32-year-old woman presents with amenorrhea, galactorrhea, and a serum prolactin of 180 ng/mL. MRI reveals a 6 mm pituitary microadenoma. The preferred drug for treatment is:
- A Cabergoline ✓
- B Bromocriptine
- C Octreotide
- D Leuprolide
Correct answer: A. Cabergoline
Explanation
Cabergoline is a dopamine agonist and is the preferred treatment for prolactinoma because of superior efficacy, better tolerability, and twice-weekly dosing compared to bromocriptine. Both drugs reduce prolactin secretion and shrink tumor size. Octreotide is used for acromegaly. Leuprolide is a GnRH agonist used for prostate cancer and precocious puberty.
Reference: Harrison's Principles of Internal Medicine, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.