Pathology · Inflammation (Acute, Chronic, Granulomatous, Mediators)

A 55-year-old man with chronic kidney disease presents with pleuritic chest pain. Auscultation reveals a pericardial friction rub. The inflammatory exudate in this condition characteristically contains abundant:

  • A Eosinophils
  • B Mucin
  • C Transudative fluid
  • D Fibrin
Correct answer: D. Fibrin

Explanation

Uremic pericarditis is a classic fibrinous inflammation: increased vascular permeability allows fibrinogen to leak into the pericardial space where it polymerizes to fibrin, producing the shaggy 'bread and butter' appearance and a friction rub. Transudate implies intact permeability, as in serous effusions. Eosinophils point toward allergic or parasitic processes, not uremic serositis.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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