A 55-year-old man with chronic kidney disease presents with chest pain that worsens when lying flat. Auscultation reveals a friction rub. Pericardial biopsy shows deposition of eosinophilic pink material over the epicardial surface with sparse inflammatory cells. Which type of inflammatory exudate does this represent?

• A Serous inflammation
• B Suppurative inflammation
• C Catarrhal inflammation
• D Fibrinous inflammation ✓

Explanation

Fibrinous inflammation results from severe injury with greater vascular permeability, allowing large amounts of fibrinogen to leak out and polymerize into fibrin. Uremia is a classic cause of fibrinous pericarditis, and the bread-and-butter appearance grossly corresponds to eosinophilic fibrin deposits microscopically. Serous inflammation implies watery, low-protein fluid, and suppurative inflammation would show prominent neutrophilic pus, both absent here.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.