In a non-endemic (sporadic) case of Burkitt lymphoma occurring in a child, the most common anatomical site of involvement is:

• A Jaw and facial bones
• B Ileocecal region of the abdomen ✓
• C Mediastinum
• D Bone marrow exclusively

Explanation

Sporadic Burkitt lymphoma most often presents as an abdominal mass involving the distal ileum, cecum, or mesentery, sometimes causing intussusception. Endemic African Burkitt characteristically involves the jaw and other facial bones. Mediastinal presentation suggests T-lymphoblastic lymphoma or primary mediastinal large B-cell lymphoma. Bone marrow involvement can occur in advanced or leukemic phases but is not the typical presenting site of sporadic disease.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.