A 50-year-old woman has abnormal uterine bleeding. Endometrial biopsy shows proliferative endometrium with cystically dilated glands, no crowding or atypia. Which is the diagnosis?

• A Simple hyperplasia without atypia
• B Complex hyperplasia without atypia
• C Disordered proliferative endometrium ✓
• D Endometrial polyp

Explanation

Disordered proliferative endometrium shows cystically dilated glands within a proliferative pattern without crowding or cytologic atypia, commonly seen in perimenopausal women with anovulatory cycles. Simple hyperplasia shows glandular crowding but no complexity. Complex hyperplasia shows back-to-back glands without atypia. Endometrial polyp is a localized lesion with thick-walled vessels and fibrotic stroma.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.