A 55-year-old man presents with a slowly enlarging, painful mass of the left pelvis. Radiograph shows an expansile lytic lesion with punctate and ring-and-arc calcifications. Biopsy confirms low-grade chondrosarcoma. What is the definitive treatment?
- A Neoadjuvant chemotherapy followed by wide excision
- B Wide surgical excision alone ✓
- C Definitive radiotherapy
- D Curettage and bone grafting
Correct answer: B. Wide surgical excision alone
Explanation
Conventional chondrosarcoma is resistant to both chemotherapy and radiotherapy. The primary treatment is wide surgical excision with adequate margins to achieve local control. Chemotherapy is reserved for dedifferentiated and mesenchymal variants. Curettage alone results in unacceptably high recurrence rates. Radiotherapy may be used for palliation in unresectable cases but is not curative.
Reference: Rosenberg AE, Chondrosarcoma, in WHO Classification of Tumours of Soft Tissue and Bone, 5th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.