According to the Enneking staging system modified for benign musculoskeletal tumours, a giant cell tumour of bone that is locally aggressive, actively growing and capable of recurrence but without metastatic potential is classified as:

• A Stage 1, latent
• B Stage 3, aggressive ✓
• C Stage 2, active
• D Stage IIB, high grade

Explanation

The benign modification of the Enneking system grades lesions as stage 1 (latent, asymptomatic, well demarcated, heals spontaneously), stage 2 (active, symptomatic, slowly enlarging, limited by reactive tissue) and stage 3 (aggressive, locally invasive, breaches barriers, recurs readily). Giant cell tumour is the classic stage 3 benign lesion, locally destructive yet rarely metastatic. Stage IIB belongs to the malignant staging system and cannot apply to a benign tumour.

Reference: Campbell's Operative Orthopaedics, 14th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.