The Ilizarov principle of distraction osteogenesis relies on which biological phenomenon as its foundation?
- A Endochondral ossification triggered by vascular ingrowth into the distraction gap
- B Tension-stress effect: gradual controlled traction on living tissues stimulates histogenesis and active growth of all tissue components including bone, vasculature, muscle and nerve ✓
- C Periosteal osteoblast activation by metal ion release from the ring fixator
- D Membranous bone formation independent of vascular supply
Correct answer: B. Tension-stress effect: gradual controlled traction on living tissues stimulates histogenesis and active growth of all tissue components including bone, vasculature, muscle and nerve
Explanation
Ilizarov's law of tension-stress (1988) states that gradual, controlled, sustained tension on living tissues creates a state of metabolic activation promoting active regeneration and growth of all tissue components — bone forms by intramembranous ossification along collagen fibres in the distraction zone (fibrous interzone), and simultaneously blood vessels, muscles, nerves, and skin undergo proportional regeneration. This underpins distraction osteogenesis for bone transport, lengthening, and deformity correction.
Reference: Maheshwari Essential Orthopaedics, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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