According to the Early Treatment for Retinopathy of Prematurity study, which combination constitutes Type 1 ROP mandating treatment within 72 hours?
- A Zone II stage 3 without plus disease
- B Any zone stage 1 or 2 without plus disease
- C Zone I any stage with plus disease, or zone I stage 3 without plus disease, or zone II stage 2 or 3 with plus disease ✓
- D Aggressive posterior ROP only
Correct answer: C. Zone I any stage with plus disease, or zone I stage 3 without plus disease, or zone II stage 2 or 3 with plus disease
Explanation
Type 1 ROP, which requires prompt laser ablation of avascular retina, comprises zone I disease at any stage with plus disease, zone I stage 3 even without plus disease, and zone II stage 2 or 3 with plus disease. Type 2 ROP (zone I stage 1 or 2 without plus, or zone II stage 3 without plus) is observed closely and treated only if it progresses to Type 1. Aggressive posterior ROP is itself treated urgently but represents only one subset, not the full definition.
Reference: Kanski's Clinical Ophthalmology, 9th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.