A premature infant born at 26 weeks gestation is screened for retinopathy of prematurity (ROP). Zone II posterior disease with plus disease and more than 5 contiguous or 8 total clock hours of stage 3 ROP is classified as:

• A Pre-threshold ROP requiring close observation only
• B Aggressive posterior ROP (APROP) requiring emergency treatment
• C Type 1 (threshold equivalent) ROP requiring treatment within 72 hours ✓
• D Type 2 ROP requiring observation every 1–2 weeks

Explanation

The Early Treatment for ROP (ETROP) study redefined treatment criteria. Type 1 ROP (should be treated within 72 hours) includes: Zone I with any stage and plus disease, Zone I with stage 3 (with or without plus), or Zone II with stage 2 or 3 with plus disease. The case described (Zone II, stage 3, plus disease with ≥5 contiguous or ≥8 clock hours) meets the ETROP Type 1 criteria. Treatment is laser photocoagulation of the peripheral avascular retina or intravitreal anti-VEGF injection (bevacizumab/ranibizumab). Aggressive posterior ROP (APROP) is Zone I or posterior Zone II flat neovascularisation with prominent plus disease.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.