A 66-year-old woman notices decreased vision six weeks after uncomplicated phacoemulsification cataract surgery. Examination shows a normal anterior segment but fundoscopy reveals cystoid spaces centred on the fovea. Fluorescein angiography shows a petalloid pattern of perifoveal leakage. What is the diagnosis?
- A Pseudophakic bullous keratopathy
- B Irvine-Gass syndrome ✓
- C Posterior capsule opacification
- D Retinal vein occlusion
Correct answer: B. Irvine-Gass syndrome
Explanation
Irvine-Gass syndrome is angiographically demonstrable cystoid macular oedema following cataract extraction, typically peaking six to ten weeks postoperatively. Inflammatory mediators released during surgery increase perifoveal capillary permeability, producing the petalloid leak on fluorescein angiography. Many cases resolve spontaneously; persistent cases are treated with topical non-steroidal anti-inflammatory drops combined with corticosteroids. Posterior capsule opacification would reduce vision earlier and show haze on slit lamp examination.
Reference: Parsons' Diseases of the Eye, 23rd ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.