In rhegmatogenous retinal detachment (RRD), the subretinal fluid accumulates between which two layers?

• A RPE and Bruch's membrane
• B Inner nuclear layer and outer plexiform layer
• C Neurosensory retina and retinal pigment epithelium (RPE) ✓
• D Nerve fibre layer and inner plexiform layer

Explanation

RRD occurs when liquefied vitreous passes through a full-thickness retinal break and accumulates in the potential space between the neurosensory retina (comprising the ten inner retinal layers) and the retinal pigment epithelium (RPE). This space corresponds to the embryological optic vesicle lumen. Subretinal fluid in CSCR also occupies this space but without a retinal break. RPE–Bruch's membrane separation occurs in AMD drusen and choroidal neovascularisation.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.