SMILE (Small Incision Lenticule Extraction) differs from LASIK in which FUNDAMENTAL structural aspect?

• A SMILE ablates the stroma using an excimer laser, LASIK does not
• B SMILE targets only the epithelium, preserving the Bowman layer
• C SMILE creates an intrastromal lenticule removed through a small incision without creating a flap ✓
• D SMILE uses a contact probe on the sclera, LASIK uses an eye tracker

Explanation

In SMILE, a femtosecond laser creates a refractive lenticule within the corneal stroma and a small (2–4 mm) arcuate incision; the lenticule is dissected and extracted without cutting a flap. This preserves more anterior stromal collagen fibres and Bowman layer integrity compared to the large flap of LASIK, potentially providing greater biomechanical strength. Both SMILE and LASIK correct refractive error by stromal reshaping; SMILE does not use an excimer laser. PRK treats the epithelium and Bowman layer.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.