Persistent fetal vasculature (PFV), formerly called persistent hyperplastic primary vitreous (PHPV), is distinguished from retinoblastoma by which feature?
- A A large, irregular intraocular mass with seeding into the vitreous
- B Calcification within the mass on CT imaging
- C Unilateral microphthalmia with a shallow anterior chamber and retrolental fibrovascular tissue ✓
- D Family history of bilateral retinoblastoma
Correct answer: C. Unilateral microphthalmia with a shallow anterior chamber and retrolental fibrovascular tissue
Explanation
PFV is typically unilateral, presents with microphthalmia, a shallow anterior chamber, and a retrolental fibrovascular membrane with elongated ciliary processes. It is a developmental anomaly of the hyaloid vasculature. Calcification and vitreous seeding are characteristic of retinoblastoma. Family history is relevant for retinoblastoma. PFV does not calcify and is distinguished by its smaller eye and characteristic retrolental membrane.
Reference: Pediatric Ophthalmology and Strabismus, AAO BCSC, 2023-2024 ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.